The antifungal effect of two biphenyl compounds, 3'-hydroxy-5-methoxy-3,4-methylenedioxybiphenyl (1) and 3'-hydroxy-5,5'-dimethoxy-3,4-methylene-dioxybiphenyl (2) against phytopathogenic fungi of rice; Bipolaris oryzae, Fusarium semitectum, Fusarium fujikuroi and Curvularia lunata was analyzed. Results of this study showed that compound 1 and 2 exhibited a very strong inhibitory activity against tested fungi with minimum inhibitory concentration (MIC) values of ≤128 g/ml. Treatment with these compounds inhibited fungal radial growth, biomass formation, and spore density. The growth inhibition resulted from these compounds is due to the lysis of fungal cells indicated by the size of mycelia, in which the size of mycelia treated with these compounds is obviously smaller than that of control.
 

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