Case Report

Long Covid Case Report: Post SARS-CoV-2 Infection Evolution in Follicular Non-Hodgkin’s Malignant Lymphoma, under Monoclonal Anti-CD20 Antibodies Treatment

Mihaela Andreescu^1,2*, Nicoleta Ilie², Andreea Lacatusu², Tudor Tony Andrei², Laura-Gabriela Tirlea², Andreea Brasoveanu², Ionescu Rozeta², Viola Popov²

¹“Department of Clinical Sciences, Hematology, Faculty of Medicine, Titu Maiorescu University of Bucharest, 040051 Bucharest, Romania
²Department of Hematology, Colentina Clinical Hospital, 01171 Bucharest, 10 Romania

*Corresponding Author's E-mail: tevetmihaela@gmail.com

Received: 15 January 2023  I  Accepted: 16 February 2023  I  Published: 18 February 2023  I  Article ID: MRJMMS23005
Copyright © 2023 Author(s) retain the copyright of this article.
This article is published under the terms of the Creative Commons Attribution License 4.0.

Abstract

Patients with malignant etiologies often exhibit unfavorable outcomes in COVID-19 infections. Due to the depleted humoral response by cytotoxic therapies and malignant conditions, such patients demonstrate prolonged shedding of SARS-CoV-2. In the current study, we present a case of 52 years old woman who presented with mild symptoms which were confirmed as SARS-CoV-2 infection by subsequent PCR test. Even after the initial correction of symptomatology, she manifested recurrent symptoms including fatigue, dyspnoea at medium efforts, coughing syndrome, and loss of appetite. Rigorous diagnostic efforts were made to identify the underlying etiology of this recurrent behavior. Our investigations revealed that the current case is not a relapse of the malignant disease but rather a prolonged case of SARS-COV-2 infection.

Keywords: Histopathology, Immunohistochemistry, Infection, Lymphoma, SARS-CoV-2