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September 2019 Vol. 7 No.9

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Rehman S
Bai S

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Merit Research Journal of Medicine and Medical Sciences (ISSN: 2354-323X) Vol. 7(9) pp. 348-352, September, 2019 

Copyright © 2019 Merit Research Journals
DOI: 10.5281/zenodo.3461137

Original Research Article

Correlation of Radiologically Diagnosed Non Alcoholic Fatty Liver with Serum Uric Acid Levels


*1Dr. Sadia Rehman, 2Dr. Santoosh Kumar, 3Dr. Fatima Mehboob, 4Dr. Fatima Rehman, 5Dr. Kapeel Raja and
Dr. Sapna Bai


1Lecturer, Department of Biochemistry, Bahria University Medical and Dental College, Karachi, Pakistan
2Department of Nephrology, Jinnah Post Graduate Medical Center, Karachi, Pakistan
3Professor of Medicine, Sharif Medical and Dental College, Lahore, Pakistan
4Lecturer, Department of Anatomy, Bahria University Medical and Dental College Karachi, Pakistan
5Assistant Professor, Pir Abdul Qadir Shah Jilani Institute of Medical Sciences Gambat, Khairpur, Sindh, Pakistan
6Department of Nephrology, Jinnah Post Graduate Medical Center Karachi

*Corresponding Authorís E-mail: dr.sadia89@hotmail.com

Accepted September 13, 2019




This study was to assess the correlation of radiologically diagnosed non alcoholic fatty liver disease with serum uric acid levels. It was a case control study conducted in a private sector tertiary care hospital in 2018. The study participants were recruited from the medicine ward while the healthy controls were taken from the general population. Non probability consecutive sampling technique was employed. Cases included were diagnosed with fatty liver through abdominal ultrasonography. Exclusion criteria was patients suffering from any other chronic illness that can lead to an echogenic liver on ultrasound (viral hepatitis and diabetes) and history of alcohol consumption. Highly significant difference was observed in mean serum uric acid levels and BMI in cases as compared to controls, with serum uric acid showing a positive linear relationship with fatty liver. Serum uric acid levels elevate with the progression of non alcoholic fatty liver disease. This finding brings a new insight of uric acid in clinical practice. Increased in serum uric acid levels might serve as a trigger for physician to screen for NAFLD.

Keywords: Non alcoholic fatty liver, serum uric acid, BMI.








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