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June 2019 Vol. 7 No.7

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Merit Research Journal of Medicine and Medical Sciences (ISSN: 2354-323X) Vol. 7(7) pp. 261-265, July, 2019 

Copyright © 2019 Merit Research Journals
DOI: 10.5281/zenodo.3352166


Nicotine Effects on Alzheimer’s Disease


Mihai Vlad Valu


University of Pitesti, Romania / Affiliation: Alexandru Ioan Cuza” University Iași, Faculty of Biology, Carol I 20A, 700605 Iasi, Romania.

E- mail: vladvalu@yahoo.com

Accepted May 11, 2019




Alzheimer’s disease (AD) is the most common neurodegenerative disorder that affects millions of people worldwide causing massive economic burden and the number of cases is expected to rise dramatically. Currently, there is no treatment that can stop or reverse the effects of AD. This review attempts to present the current status of research, biopathological approach mechanisms, and nicotine as a therapeutic method in AD. Nicotine has been related to recovery of memory in humans and animal models and some observational studies have been compatible with a protective effect of nicotine inhalation against Alzheimer’s disease. At present, there is great controversy over this possible effect of tobacco use, and evidence is inconclusive.

Keywords: Nicotine, Alzheimer’s disease, Anxiety, Depression, Diagnostic







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