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August 2018 Vol. 6 No.8

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Patoli MV
Tanwir F

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Merit Research Journal of Medicine and Medical Sciences (ISSN: 2354-323X) Vol. 6(8) pp. 278-283, August, 2018 

Copyright © 2018 Merit Research Journals

Original Research Article

Don’t Judge Disability with its Visibility: Gender Variation in Frequency of Rheumatoid Arthritis with its Clinical Parameters


Dr. Misbah Vaqar Patoli3*, Dr. Fasiha Sohail2*, Dr. Sumera Nawaz, Dr. Muhammad Fahad Zakir1*, Dr. R. Annum Rahim, Dr. Ghania Niazi and Dr. Farzeen Tanwir


1Post Graduate Trainee, Department of Medicne, Ziauddin University and Hospital, Karachi, Pakistan
2Assistant Professor, Department Of Medicne, Ziauddin University and Hospital, Karachi, Pakistan
3Post Graduate Trainee, Department of Medicne, Ziauddin University And Hospital, Karachi, Pakistan

*Corresponding Authors’ E-mail: farzeen.tanwir@utoronto.ca

Accepted August 11, 2018




The Objectives of this study is to determine the frequency of clinical features of rheumatoid arthritis in males and females in local population of Karachi. A descriptive prospective was conducted in tertiary care hospital in Karachi from August 1, 2017 till February 28, 2018.Careful selection of patient based on their clinical presentation and initial laboratory workup for RA factor was done and treated on the line of Rheumatoid arthritis and followed up in OPD for response with treatment. A total of 1600 patients were enrolled for study. Total of 1438 patients participated in the study and 162 patients were lost to follow up after discharge from hospital. Females were found to be predominant as compared to males. Majority of sample size was found in age group 21-40 and 40-61 years of age. RA factor was found negative in most of cases. Rheumatoid arthritis is a heterogeneous disease with gender variability. Sex related factors influence disease activity and severity, it should be considered as treatment responses and side effects may vary in both. In our study predominantly females of reproductive and middle age group reported to have clinical symptoms but found to have negative laboratory results.

Keywords: Disability, Visibility, Gender variation, Rheumatoid Arthritis







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