December 2016 Vol. 4 No.12

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Original Research Article

Prognostic Value of Successful Percutaneous Coronary Intervention in Patients with Chronic Total Coronary Occlusion

Abdalla Mostafa Kamal¹, Ahmed Mohamed Emara^1*, Aladdin Abd El-Aty Bahy²

¹Dept. of Cardiology, Faculty of Medicine, Menoufia University, Egypt
²Mahalla Cardiac Centre, Mahalla, Egypt

*Corresponding Author’s E-mail: am.emara@yahoo.com

Accepted December 03, 2016

Abstract

Chronic Total Occlusion (CTO) of coronary arteries remains one of the most challenging lesion subsets in interventional cardiology even with the development of medical devices and operator experiences. Successful revascularization results in clinical improvement, symptom relief and enhanced left ventricular function and reduces the need for Coronary Artery Bypass Grafting (CABG) surgery. This study sought to assess prognostic value and clinical outcome of successful percutaneous coronary intervention in patients with chronic total coronary occlusion. In this study, clinical and coronary angiography data of (60) patients with CTO between January 2012 and September 2015 where (30) patients underwent successful Percutaneous Coronary Intervention (PCI) with drug-eluting stent and the other (30) received medical treatment only. Patients must have evidence of viable myocardium. All patients underwent clinical and laboratory evaluation. Follow up for six months after the procedure for major adverse cardiac events and clinical outcome. The successful PCI group included 22 males (73.30%) and 8 females (26.7%). The conservative group included 23 males (76.7%) and 7 females (23.3%), no significant difference was found between both groups; P = 0.766. The mean age of the successful PCI group was 51.87± 6.63 years and that of conservative group was 50.93±5.60 years, no significant difference was found between both groups; P = 0.558. After six months angina CCS class, NYHA class and left ventricular function significantly improved in the successful PCI group compared to the conservative group. Successful revascularization of CTO leads to clinical improvement, symptom relief and enhanced left ventricular function.

Keywords: Coronary angiography data, Chronic total occlusion, Percutaneous coronary intervention, Prognostic value