December 2016 Vol. 4 No.12

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Review

Periorbital Nodular Fasciitis in an Adult Male: The First Reported Case in the Middle East with Review of the Literature

Hind Manaa Alkatan, MD^1,3*, Abdullah Ibrahim Almater², Khaldoon Aljerian, MHSc, FRCPC³ and
Yasser H Al-Faky, MD, FRCS¹

¹Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia
²Medical Student, College of Medicine, King Saud University, Riyadh, Saudi Arabia
³Department of Pathology, College of Medicine, King Saud University, Riyadh, Saudi Arabia

*Corresponding Author’s E-mail: hindmkatan@gmail.com hkatan@ksu.edu.sa
Tel: +966504492399
Fax: +966112052740

Accepted November 26, 2016

Abstract

Nodular fasciitis (NF) is a benign, fibroblastic proliferation, which can raise suspicion for malignancy and is relatively rare in the ocular region. We report the first case of periorbital NF in the Middle East with review of the literature. Our case of NF is described clinically and histopathologically in detail. An extensive review of all reported cases of ocular/periocular NF in the English-written literature is made with summary of 39 cases including ours taking into consideration the location of the tumor, age and gender. Our 35-year-old male presented with a recurrent tumor in the periocular region. Diagnosis of NF was made by careful histopathological examination of the excisional biopsy and by immunohistochemical staining. We have summarized the demographics and tumor location of 38 cases previously reported and added our case information. Demographically, NF occurs within a wide range of age (8months to 81years) with a mean age of about 28 years. Half of the cases are in the age group of 30 years or younger (median=30 years). Slight female predominance is observed (F:M =7:6). The right side is more commonly involved (in 21/37). Periocular/orbital involvement is more commonly found (67%).

Keywords: Nodular Fasciitis, Ocular, Periocular