The aim of this research is to evaluate the effects of cuprous oxide preparations of Kushta on renal function tests. This study was conducted at Pathology Department of University of Health Sciences Lahore and it was an experimental study. Thirty albino rats were selected and divided into three groups. The control group A was fed on standard pellet rodent diet and tap water. The experimental group B was fed single dose of cuprous oxide preparation of Kushta (0.15mg/kg of body weight) for 24 weeks while experimental group C was fed double dose of cuprous oxide preparation of Kushta (0.5mg/kg of body weight) for 24 weeks. Renal function tests were calculated once at the start of experiment and then after every 6 weeks up to 24 weeks. Results showed that renal function tests in terms of serum creatinine level and proteinuria were deranged evident on biochemical analysis. When the Control group A on normal diet was compared with the experimental group B and C, statistically significant difference (p<0.05) was noticed in terms of renal function tests. It is therefore concluded that cuprous oxide preparations of Kushta deranged renal function tests in terms of serum creatinine levels and proteinuria.
 

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