Buscopan (Hyoscine-N-butylbromide) is a widely used antispasmodic agent in obstetric practice for alleviating cervical spasm and facilitating cervical dilation during labour. However, knowledge and attitudes regarding its use among pregnant women remain underexplored in Nigeria. This study sought to assess the knowledge and attitude of pregnant women towards the use of Buscopan in the management of labour at Abia State University Teaching Hospital (ABSUTH), Aba, Nigeria. A descriptive cross-sectional survey was conducted among 422 pregnant women attending antenatal clinics at ABSUTH. Participants were systematically selected and data were collected using a structured, pretested, interviewer-administered questionnaire. Descriptive statistics were used to summarize socio-demographic characteristics, knowledge, and attitudes. Inferential statistics including Chi-square and Spearman's rank correlation were applied to examine associations. Significance was set at p < 0.05. Out of 422 respondents, 65.9% had heard of Buscopan, but only 34.6% correctly identified its use in aiding cervical dilation. While 54.3% acknowledged its ability to reduce cervical spasm, only 33.4% were aware of its side effects. Attitudinally, 75.1% agreed or strongly agreed that Buscopan is helpful during labour, yet 50.2% expressed concerns about potential harm. A strong positive correlation was observed between knowledge and attitude scores (ρ = 0.61, p < 0.001). Educational level, parity, and source of information were significantly associated with knowledge and attitudes towards Buscopan (p < 0.05). Although awareness of Buscopan is moderately high among pregnant women in ABSUTH, significant gaps in specific knowledge and mixed attitudes exist. Improved antenatal education and communication by healthcare providers are recommended to enhance informed decision-making and acceptance.

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