The term "disaster" a widespread destruction of the environment, economics, healthcare, and social infrastructure that may disrupt the individuals' or whole communities' ability to use their resources to overcome such events. Disaster preparedness usually includes a variety of activities, programs, and systems that should be implemented before an event occurs. As soon as such policies are developed, they should be implemented into the healthcare system and all healthcare workers should be trained in their implementation. The current study investigated emergency preparedness and factors which may affect healthcare workers' readiness at the National Center of Disaster Management in Riyadh district. This study used a descriptive cross-sectional design. The survey was conducted in December 2022 on an online platform with primary data collection and a non-probabilistic purposive sample. The study involved 80 healthcare workers from the National Center for Disaster Management in Riyadh district. The responses were quantified using descriptive statistics including frequencies, means, percentages, and standard deviations. According to the survey, 41 (51.2%) of respondents reported they were somewhat prepared, while 22 (27.5%) reported they were somewhat unprepared. More than one-quarter of the healthcare workers 23 (28.7%) did not take any training in disaster management. There were some gaps in disaster preparedness among healthcare providers. In the study, healthcare workers did not perceive themselves as fully prepared for disasters and were unaware of disaster management protocols. During disaster preparedness, recommendations are made for enhancing clinical and educational efforts in healthcare workplaces.