Arterial Blood Gases Interpretation is one of the most important studies in critical care, as it directs doctors in the right path for a better diagnosis, treatment, and projected result of the illnesses in question. Because nurses are the primary care providers in critical care units, their understanding of ABGs interpretation and analysis could be essential in the management of very ill patients with respiratory, cardiovascular, acid-base, and renal disorders. The main objective of this study was to assess nurse’s knowledge regarding ABGs interpretation. A cross sectional study was conducted on 134 nurses at University of Lahore Teaching Hospital Lahore. A reliable and verified questionnaire was used to collect data. Data was analyzed by using spss-25. According to result of the study 4(3.0%) nurses out of 134 nurses was excellent knowledge regarding ABGs interpretation, 5(3.7%) nurses out of 134 was good knowledge regarding ABGs interpretation, 40(29.9%) nurses out of 134 was moderate knowledge regarding ABGs interpretation and 85(63.4%) nurses out of 134 was poor knowledge regarding ABGs interpretation. The result of the this study was depict that majority of the nurses 85(63.4%) had poor knowledge regarding ABGs interpretation. The study conclude that structured teaching programme had significant effect on nurse knowledge regarding arterial blood gases analysis and interpretation
 

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