This study investigated knowledge and acceptability of cervical cancer screening among female health education students of AlvanIkoku Federal College of Education, Owerri. The study was guided by 5 research questions. The study adopted a cross-sectional descriptive design. The target population for the study will comprise of 603 of AlvanIkoku Federal College of Education Owerri. A systematic random sampling method will be used to select 274 students from all the four levels of health education students in AlvanIkoku Federal College of Education Owerri using Taro Yamane’s formular (1997). The instrument used for data collection was a self-structured questionnaire. The instrument was validated by experts and the reliability of the instrument was conducted. Data from the study was analysed using descriptive statistics such as frequencies, percentages, mean and standard deviation. Findings from the study revealed that there is high level of knowledge of CC screening among female health education students of AlvanIkoku Federal College of Education, Owerri. The study further revealed that there is a high level of acceptability of CC screening among female health education students of AlvanIkoku Federal College of Education, Owerri. More still, Healthcare providers, health education classes/curriculum, online resources, family members, friends, television, radio programs, printed materials, community health events and social media campaigns are the sources of Information about CC Screening among female health education students of AlvanIkoku Federal College of Education, Owerri. Additionally, female health education students of AlvanIkoku Federal College of Education, Owerri are willing to Undergo CC Screening to a high extent. Finally, the study revealed that knowledge of cc and screening benefits, family and friend support, among others are the factors influencing the knowledge and acceptability of CC screening among female health education students of AlvanIkoku Federal College of Education, Owerri. Based on the findings, the study recommended among others Integrating CC screening education into the health education curriculum at AlvanIkoku Federal College of Education, Owerri, to increase knowledge and awareness among students.

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