Many smokers with chronic diseases that are clearly worsened by cigarette smoking fail to quit in spite of their repeated attempts. One reality is that not all smokers, even in the face of debilitating disease, can stop smoking. To assess the success/failure rates for quitting cigarette smoking as well as to identify risk factors for failure to maintain smoking abstinence for more than 12 months among male Saudis attending the “Anti-Smoking Clinic” in Abha City. This study followed a cross-section design conducted in Abha city. The study included all ex-smokers registered for at the Anti-Smoking Clinic for at least one year. A data collection sheet was utilized. It includes personal characteristics, clinical picture and investigations, received treatment, and status of cigarette smoking quitting.