Blood transfusion is a life-saving and highly effective treatment. Errors in blood and blood product transfusion can lead to unnecessary morbidity and mortality. Nurses have a critical role to play in ensuring patient safety throughout blood transfusions. A descriptive cross sectional study was used in this study. Convenient sampling was used for data collection. Sample size was 120 from the University of Lahore. Conduct and utilization of research in nursing questionnaires was used for nurses’ knowledge regarding hemovigilance. Data analysis was done by entering the data on Spss software. The findings of study revealed that the majority of participants 57.5% had an inadequate knowledge regarding blood transfusion, 30% had a moderate knowledge and 12.5% had poor knowledge regarding the monitoring of each step of blood transfusion and adverse blood transfusion reaction management. The majority of nurses had insufficient knowledge of all four phases of blood transfusion, in which nurses played a significant role in monitoring each step of the process and managing adverse blood transfusion reactions.
 

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