To investigate the enormity of prostate cancer in the North West-Bank, and shed light on underlying risk factors affecting its distribution. We performed a retrospective study among hospitalized patients in West-Bank. 70.000 men aged 40 years or older were our study target. Analysis was based on patient admissions, and statistical methods (ANOVA Test, T-test, Correlation, Chi squire test, Descriptive statistics and frequencies and percentile methods) were used. 78 prostate cancers were reported with incidence rate of 10.4 per 100.000 populations. We revealed that the majority of patients (64.1%) were diagnosed in Nablus town and the lowest (6.4%) in Tulkarem town. Risk factors such as type of occupation, number of children, Age and obesity, showed a Pearson correlation and statistical significance at P-Value = 0.05 which was respectively (p=0.016, p=0.018, p= 0.003, p=0.004). Significant relationship was found between age and infection (P-value = 0.032) and between cancer stage and age (0.021). Prostatic carcinoma strikes disproportionately in different regions in west-Bank, employment types, extended families; aging and obesity were found to be risk factors and vegetarian diet as protective factor. However, lower prevalence was observed when we compared our results with Western Countries. Impact Screening with PSA testing, digital rectal examination and traditional Mediterranean diets with lower consumption of saturated fat altogether may decrease, and hold the promise for early detection and sustained decline in prostate cancer mortality.