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March 2019 Vol. 7 No.3

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Rafla S
Elhoshy S

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Merit Research Journal of Medicine and Medical Sciences (ISSN: 2354-323X) Vol. 7(3) pp. 112-118, March, 2019 

Copyright © 2019 Merit Research Journals
DOI: 10.5281/zenodo.2604724

Original Research Article

Study of the diagnostic and therapeutic challenges in patients with coexistent chronic obstructive pulmonary disease and chronic heart failure


Samir Rafla, Ali Hassan Aboelhoda, Rania Ahmed Swied*, Azza Ahmed Khamis and
Mohamed Saeed Elhoshy**


Alexandria University, Faculty of Medicine, Cardiology Department, Chest Department* and Research Institute**, Egypt

*Corresponding Author: Samir Rafla
E-mail: smrafla@yahoo.com

Accepted March 23, 2019




The aim of this study was to determine the impact of chronic obstructive pulmonary disease treatment on the clinical condition of patients with heart failure. Forty Patients were enrolled in this study with chronic obstructive pulmonary disease co-existent with heart failure (EF <50%). All patients enrolled in this study were males (100%). Most of the studied patients (40%) were aged between 61 and 70 years old. Definition of COPD: when FEV1 was less than 70%. About smoking: 25 patients stopped smoking (62.5%), and 15 patients didn’t stop smoking (37.5%). Risk factors: 34 patients (pts) (85%) suffered from systolic hypertension, 18 pts (45%) suffered from diabetes, and 28 pts (70%) had dyslipidemia. All patients were smokers (97.5%) except 1 patient was passively smoking and 17 patients were NYHA class III (42.5%), 23 patients were NYHA class II. Average weight and height of studied patients was 88.1 ± 14.7kg and 172.5 ± 7.7cm respectively. Mean body mass index (weight/ (height) 2) was 29.2 ± 6kg/m2. ECG findings: Among studied patients, ischemic changes in ECG were present in 37 cases (92.5%). Improvement of COPD is associated with improvement of heart failure. Cessation of smoking is the best marker of possible improvement of both diseases. The use of sympathomimetics as inhalers or tablets had no deleterious effect on cardiac function.

Keywords: Spirometry, Chronic Obstructive Pulmonary Disease (COPD), Heart Failure, Smoking, Sympathomimetic inhalers







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