Home About Us Writing a Scientific Article Author's Instruction Contact us
 

MERIT RESEARCH JOURNAL OF MEDICINE AND MEDICAL SCIENCES (MRJMMS) (ISSN: 2354-323X)

 
 

/  /    MRJMMS Home   /   /    About MRJMMS    /  /    Submit Manuscripts    /  /      Call For Articles      / /     Editorial Board     / /    Archive     / /    Author's Guide  /  /

 
 


February 2019 Vol. 7 No.2

Other viewing option


Abstract
• Full text
•Reprint (PDF) (84 KB)

Search Pubmed for articles by:
 

Alzahrani AH
Kinsara J

Other links:
PubMed Citation
Related articles in PubMed


















































































































































 




 

Merit Research Journal of Medicine and Medical Sciences (ISSN: 2354-323X) Vol. 7(2) pp. 054-057, February, 2019 

Copyright © 2019 Merit Research Journals
DOI: 10.5281/zenodo.2571543


Original Research Article

Prevention of Infective Endocarditis, should Developing Country have Concern with the Guidelines?

 
 
 

Atif H. Alzahrani1, Mona A. Kholeif1, Abeer Al Shukairi2, Areej Mufti3 and Abdulhalim Jamal Kinsara1*

 

1Department of cardiology, Ministry of National Guard health Affair, Jeddah, Saudi Arabia. King Abdullah International medical research center, King Saud Bin Abdulaziz University for Health Sciences, COM-WR
2Infectious Diseases Department- King Faisal Specialist Hospital and Research Center,
3Microbiology Division, Department of Pathology and Laboratory Medicine, At King Saud bin Abdulaziz University for Health Sciences, COM-J. King Abdul Aziz Medical City-WR.

*Corresponding Author’s Email: kinsaraaj@ngha.med.sa
Tel 966-12-2266666, ext. 25797

Accepted February 12, 2019

 

Abstract

 

The published guidelines of Infective endocarditis (IE) markedly restricting the use of antibiotic prophylaxis for prevention of IE resulted in some controversy. The aim of this study is to attempt to answer the question – Should the developing country have a concern of rising incidence of IE with the current guidelines? Retrospective analysis of all reported cases of definitive IE based on modified Duke Criteria in tertiary hospital over a 5-year period. 20 reported cases of IE, 9 males (45%) and 11 females, mean age 36 years (12 days- 72 years); one patient had history of rheumatic heart disease, 4 patients (20%) had congenital heart disease. 14 patients (70%) had history of a prior procedure. Blood cultures were positive in 16 patients (80%), with culture-negative IE in 4 patients. The most common organisms were Staphylococcus spp. In 9 patients (45%), Enterococcus spp. Was isolated in 2 patients (10%), Gram negative bacilli isolated in 2 patients, one Enterobacter and one Acinetobacter bummani. There was one case of streptococcal IE, the usual target for prophylactic antibiotics and the patient had received prophylactic antibiotics peri-procedurally. Most organisms were acquired nosocomially and/or after procedures which did not require prophylactic antibiotics under any previous or current guidelines. IE is uncommon disease in our practice representing only 0.017% of total admissions and complicating only one dental procedure out of 101,825. The current guidelines for IE antibiotic prophylaxis did not carry extra risk in developing country, but preferably we may continue to collect relevant data.

Keywords: Infective Endocarditis, developing country, Antibiotic Prophylaxis

 









































































 










 







































 










 

 
 
   
   
   
   
   
   
   
   
   
   
   
 
 
 
 
 
 
 
 
   
 
                         

Merit Research Journals© 2019 || Advertisement | Privacy policy.