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March 2017 Vol. 5 No.3

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Burcel M
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Merit Research Journal of Medicine and Medical Sciences (ISSN: 2354-323X) Vol. 5(3) pp. 142-148, March, 2017 

Copyright © 2017 Merit Research Journals


Original Research Article

Efficiency evaluation of corneal collagen crosslinking intervention in patients with keratoconus

 
 
 

Miruna Burcel1*, Catalina Corbu1,3, Vasile Potop1,3, Mihaela Constantin2, Dana Dascalescu1, Catalina Ionescu1, Valeria Coviltir1,3, Marian Burcea1,3, Radu Ciuluvica5 and Liliana Voinea3,4

 

1Clinical Hospital of Ophthalmologic Emergencies, Piata Alexandru Lahovari1, Bucharest, Romania
2Oftaclinic, Bucharest, Romania
3Division of Ophthalmology, Faculty of Medicine, “Carol Davila” University of Medicine and
Pharmacy, Bulevardul Eroii Sanitari 8, 050474, Bucharest, Romania
4Departament of Ophthalmology, University Emergency Hospital, SplaiulIndependetei 169, 050098, Bucharest, Romania
5Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bulevardul Eroii Sanitari 8, 050474, Bucharest, Romania

*Corresponding Author Email: cristea.miruna@yahoo.com
Tel.: no. +40767571423

Accepted February 24, 2017

 

Abstract

 

The purpose of the paper is to evaluate the safety and efficiency of corneal collagen crosslinking (CXL) intervention in patients with progressive keratoconus. This study included patients having different evaluative stages of keratoconus, showing eligibility criteria for the crosslinking technique. The procedure has been applied to 90 eyes of 72 patients; corrected and uncorrected visual acuity, corneal thickness values and topographic aspects were recorded before and after intervention. Visual acuity improved for the majority of cases. The average decrease of the maximum keratometric values was 1.51±1.85 dioptres. Among the patients who underwent crosslinking, 5 met the criteria for progression and 2 of them underwent redo CXL. Corneal collagen crosslinking is the therapeutic method for increasing corneal biomechanical stability by binding new links between collagen fibrils using ultraviolet light and riboflavin as photo sensibilising agent. A close follow-up is necessary after the procedure. Risk factors associated with progression after primary CXL remain unclear and more studies are needed to clarify it.

Keywords: Corneal collagen crosslinking, Keratoconus, Keratometry, Pachimetry, Topography

 










 







































 










 

 
 
   
   
   
   
   
   
   
   
   
   
   
 
 
 
 
 
 
 
 
   
 
                         

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