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July 2017 Vol. 5 No.7

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Merit Research Journal of Medicine and Medical Sciences (ISSN: 2354-323X) Vol. 5(7) pp. 331-336, July, 2017 

Copyright © 2017 Merit Research Journals


Original Research Article

Clinical profile and factors associated with treatment outcome in tuberculosis in children in Kinshasa, Democratic Republic of Congo

 
 
 

Aketi Loukia1*, Shiku Diayisu Joseph1, Bakoko Bryan2, Anshambi Nicole3, Kashongwe Zacharie4 and Kayembe Kalambay Patrick5

 

1Department of Pediatrics, University Hospital of Kinshasa, Kinshasa, Democratic Republic of Congo
2National Tuberculosis Program, Provincial Coordination, Kinshasa, Democratic Republic of Congo
3Student at the Public Health School at the University of Kinshasa, Kinshasa, Democratic Republic of Congo
4Department of Internal Medicine, University Hospital of Kinshasa, Kinshasa, Democratic Republic of Congo
5Epidemiology and Biostatistics Department, Public Health School at the University of Kinshasa, Kinshasa, Democratic Republic of Congo

*Corresponding Author’s E-mail: akelou@yahoo.fr

Accepted June 23, 2017

 

Abstract

 

The aim of our study is to evaluate the clinical profile of tuberculosis (TB) patients and identify factors associated with treatment outcomes in Kinshasa. A retrospective and multicenter study of children aged 0 to 15 years who presented with TB from January 2010 to December 2014 at 18 TB unit in Kinshasa was conducted. A total of 2500 cases were included [average age: 6.8 (± 4.7) years]. The majority, 1350 (54 %), had EPTB and 1150 (46 %) had PTB [834 (33.36 %) clinically diagnosed and 316 (12.64 %) bacteriologically diagnosed]. Concerning the treatment outcomes, 2094 (83.8 %) cases completed treatment, 295 (11.8 %) cases were cured, 34 (1.4 %) cases were transferred, 48 (1.9 %) cases defaulted, 21 (0.8 %) cases died, and 8 (0.3 %) cases were failed, then the treatment success (cure/treatment completion) was represented by 2389 (95.6 %) cases, and the poor outcome (defaulter/deceased/failure) was encountered in 77 (3.1 %) cases. There was a significant association (P=0.001) between the form of TB and treatment outcome. The chi-square of tendency showed that having PTB+ was associated with 2 times greater risk of poor outcome. The treatment success rate was appreciable in Kinshasa, but there is a need to improve the diagnosis of childhood TB.

Keywords: Tuberculosis; Children; Clinical profile; Outcome; Kinshasa













 










 







































 










 

 
 
   
   
   
   
   
   
   
   
   
   
   
 
 
 
 
 
 
 
 
   
 
                         

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